Breast /ovarian cancer –genetic predisposition BRCA1 -5382insC.4153delA, C61G
Analysis ID 7
Analysis location “GENESIS” Centre for Medical Genetics
Diagnosed illness Breast /ovarian cancer –genetic predisposition BRCA1 -5382insC.4153delA, C61G
OMIM #604370
Clinical information Clinical strong genetic predisposition to mammary gland and ovarian cancer is usually connected with constitutive mutation in the BRCA1 and BRCA2 gene. It appears mostly with hereditary breast cancer - site specific HBC-ss or hereditary breast-ovarian cancer HBOC or hereditary ovarian cancer HOC. Due to high genetic homogeneity of the Polish population, predisposition to mammary gland and ovarian cancer comprises carrier testing of 3 most common mutations in the BRCA1 gene: 5382insC, 4153delA, 300T/G.
Type of analysis Molecular
Type of biological material 5-10 ml peripheral blood collected in the EDTA tube
Analyzed genes BRCA1
Analysis description Genetic carrier analysis of three most common mutations in the BRCA1 gene.
Analysis indication Analysis is recommended to an adult person with familial hereditary breast/ovarian carcinomas, as well as to young woman, who consider initiating on oral contraceptives.
Analysis time 3-4 weeks
Refund Yes
CGM laboratory name Laboratory of Molecular Genetics and Oncology