Rak - genetyczna predyspozycja, badanie nosicielsta mutacji markerowej CHEK2 (1100delC, IVS2+1GA)
Analysis ID 17
Analysis location
Diagnosed illness Rak - genetyczna predyspozycja, badanie nosicielsta mutacji markerowej CHEK2 (1100delC, IVS2+1GA)
OMIM
Clinical information
Type of analysis Molecular
Type of biological material 5-10 ml of peripheral blood collected in an EDTA tube
Analyzed genes CHEK2
Analysis description Changes resulting in truncated CHEK2 protein (1100delC and IVS2+1G>A) increase 2,4 times the risk for breast cancer (mostly lobular cancer) and occur in 2,5% of all breast cancers; increase 2,3 times risk for prostate cancer and occur in 2,5% of all prostate cancers; increase 5 times risk for prostate cancer if a first-degree relative is affected. The changes increase 5 times the risk for thyroid cancer and occur in 4% of papillary thyroid cancers.
Analysis indication
Analysis time 3-4 weeks
Refund No
CGM laboratory name