Melanoma, lung, colon cancer – susceptibility to (CDKN2A (p16)
Analysis ID 21
Analysis location “GENESIS” Centre for Medical Genetics
Diagnosed illness Melanoma, lung, colon cancer – susceptibility to (CDKN2A (p16)
OMIM 155601
Clinical information A148T change in the CDKN2A gene increases 2 times the risk of melanoma and appears in 7% of all malignant melanomas. Risk of breast cancer (DCIS) before 50 year of age is increased 1,5 times (the mutation occurs in 5% of all breast cancers before the age of 50). Additionally, A148T increases 2 times the risk for lung cancer (A148T occurs in the 7% of all lung cancers), and 1,5 times for colon cancer (A148T appears in the 5% of all colon cancers).
Type of analysis Molecular
Type of biological material 5-10 ml peripheral blood collected in the EDTA tube
Analyzed genes CDKN2A (p16)
Analysis description predisposition to CDKN2A
Analysis indication
Analysis time 3-4 weeks
Refund No
CGM laboratory name Laboratory for molecular genetics and oncology