Deafness, Aminoglycoside-inducted
Analysis ID 297
Analysis location “GENESIS” Centre for Medical Genetics
Diagnosed illness Deafness, Aminoglycoside-inducted
OMIM #580000
Clinical information The mechanism of ototoxicity of aminoglycosides is thought to be caused by their interference with the production of ATP in the mitochondria of hair cells in the cochlea. Among many, the aminoglycosides include f. e. kanamycin, gentamicin, tobramycin, neomycin, and streptomycin.
Type of analysis Molecular
Type of biological material 5 ml of peripheral blood collected in an ETDA tube; DNA sample
Analyzed genes 12S rRNA
Analysis description Analysis consists of sequencing of the mitochondrial DNA genes
Analysis indication Deafness inducted by aminoglycosides
Analysis time 3 – 4 weeks
Refund No
CGM laboratory name Laboratory for diagnostics of the hereditary disorders